Maitake Extract Research Summary
Considered a gourmet mushroom, Maitake is also an important medicinal mushroom in Oriental medicine. It is especially known for its high content of beta-glucans [71, 72], which are known as potent immune boosters.
The common English name for Maitake is Hen-of-the-woods, due to its occasional resemblance to the fluffed up tail feathers of a hen. It is one of the most easily recognizable edible mushrooms in North America, though it is only to be found in eastern Canada and U.S. down to the Mid-Atlantic States.
Research has found Maitake extract to increase tumor necrosis factor [73, 74, 75] and demonstrate other anti-tumor properties. [76, 77, 78, 79, 80, 81] Specific focus in these studies has been given to breast, prostate, lung, liver and colorectal cancer. [82] In fact, a Phase II study of Maitake on breast and prostate cancer was approved by the FDA. [83]
Other Maitake research has focused on its ability to enhance the immune system, both in general [84, 85, 86] as well as in cancer patients. [87] The anti-viral potential of Maitake extract has been of particular interest. [88] Viruses are, after all, notoriously difficult to treat. Research on Maitake and HIV is being conducted. [89]
Blood sugar is another area where Maitake extract appears to have an effect. In one study, insulin-resistant individuals that were administered Maitake experienced an average 25% blood-glucose drop. [90, 91, 92]
In addition to research on Maitake extract, there are also many studies on the individual active compounds, in particular beta-glucans. A patent application exists on “Methods of using beta glucan as a radio-protective agent.” The patent in question “relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity.” [93] This protective effect against radiation poisoning and degradation of the immune system may be why NASA gives beta-glucans to astronauts.
Additional therapeutic properties of Maitake extract as indicated by scientific research include: anti-bacterial, anti-Candida, moderating blood pressure, respiratory conditions, nerve tonic, and stress reducer. [25]
Medicinal mushroom expert Paul Stamets, in his book Mycelium Running, also lists Maitake extract as showing some positive effect on leukemia. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner.
Credit to Paul Stamets for research and source material.
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